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Chemical Structure : Cangrelor tetrasodium
Catalog No.: PC-61585Not For Human Use, Lab Use Only.
Cangrelor (AR-C69931MX) is a potent, selective P2T/P2Y12 receptor antagonist with IC50 of 0.4 nM against ADP-induced aggregation of human platelets.
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Cangrelor (AR-C69931MX) is a potent, selective P2T/P2Y12 receptor antagonist with IC50 of 0.4 nM against ADP-induced aggregation of human platelets; displays >1,000-fold selectivity over other P2 receptor family; antagonizes the ex vivo and in vivo aggregatory actions of ADP, and displays a rapid onset and offset of action with the ability to prevent occlusive arterial thrombus formation.
Thrombosis
Approved
| M.Wt | 864.29 | |
| Formula | C17H21Cl2F3N5Na4O12P3S2 | |
| Appearance | Solid | |
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| Solubility |
10 mM in DMSO |
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1. Ingall AH, et al. J Med Chem. 1999 Jan 28;42(2):213-20.
2. Huang J, et al. J Pharmacol Exp Ther. 2000 Nov;295(2):492-9.
3. Storey RF, et al. Br J Haematol. 2000 Sep;110(4):925-34.
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