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Chemical Structure : Capromorelin
CAS No.: 193273-66-4
Catalog No.: PC-38623Not For Human Use, Lab Use Only.
Capromorelin (CP-424391) is a pyrazolinone-piperidine dipeptide growth hormone secretagogue and ghrelin receptor agonist with Ki value of 7 nM (hGHS-R1a), and EC50 vaule of 3 nM (rat pituicyte).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $138 | In stock | |
| 10 mg | $198 | In stock | |
| 25 mg | $328 | In stock | |
| 50 mg | $528 | In stock | |
| 100 mg | Get quote |
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Capromorelin (CP-424391) is a pyrazolinone-piperidine dipeptide growth hormone secretagogue and ghrelin receptor agonist with Ki value of 7 nM (hGHS-R1a), and EC50 vaule of 3 nM (rat pituicyte).
Capromorelin (CP-424391) increased plasma GH levels in an anesthesized rat model, with ED(50) values less than 0.05 mg/kg iv.
Capromorelin showed enhanced intestinal absorption in rodent models and exhibited superior pharmacokinetic properties, including high bioavailabilities
| M.Wt | 505.619 | |
| Formula | C28H35N5O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-amino-N-((R)-1-((R)-3a-benzyl-2-methyl-3-oxo-2,3,3a,4,6,7-hexahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)-3-(benzyloxy)-1-oxopropan-2-yl)-2-methylpropanamide |
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1. Carpino PA, et al. Bioorg Med Chem Lett. 2002 Nov 18;12(22):3279-82.
2. Pan LC, et al. Endocrine. 2001 Feb;14(1):121-32.
3. Carpino PA, et al. Bioorg Med Chem. 2003 Feb 20;11(4):581-90.
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