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Cardionogen 1

Chemical Structure : Cardionogen 1

CAS No.: 577696-37-8

Cardionogen 1 (CDNG1)

Catalog No.: PC-62447Not For Human Use, Lab Use Only.

Cardionogen 1 (CDNG1) is a small molecule that promotes cardiomyocyte generation by modulating Wnt signaling.

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    Biological Activity

    Cardionogen 1 (CDNG1) is a small molecule that promotes cardiomyocyte generation by modulating Wnt signaling.
    Cardionogen 1 inhibits Wnt/β-catenin-dependent transcription in murine ES cells and zebrafish embryos.
    Cardionogen 1 rescues Wnt8-induced cardiomyocyte deficiency and heart-specific phenotypes during development.

    Physicochemical Properties

    M.Wt 274.342
    Formula C13H14N4OS
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    6-Cyclohexyl-3-furan-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole

    References

    1. Ni TT, et al. Chem Biol. 2011 Dec 23;18(12):1658-68.

    2. Yan C, et al. Sci Rep. 2017 Apr 5;7:45796.

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