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Cedirogant

Chemical Structure : Cedirogant

CAS No.: 2055496-11-0

Cedirogant (ABBV-157, ABBV157)

Catalog No.: PC-38349Not For Human Use, Lab Use Only.

ABBV-157 (Cedirogant) is a small molecule inhibitor (inverse agonist) of RORγT being investigated for the treatment of immune-mediated diseases (e.g. Psoriasis).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

ABBV-157 (Cedirogant) is an orally bioavailable small molecule inhibitor (inverse agonist) of RORγT being investigated for the treatment of immune-mediated diseases (e.g. Psoriasis).

Physicochemical Properties

M.Wt 547.780
Formula C24H20Cl3F3N2O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(1-(2,4-dichloro-3-((7-chloro-5-(trifluoromethyl)-1H-indol-1-yl)methyl)benzoyl)piperidin-4-yl)acetic acid

References

1. Christian Gege. Expert Opin Drug Discov. 2021 Dec;16(12):1517-1535.

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