Centanafadine (EB-1020) | Triple reuptake inhibitor

Chemical Structure : Centanafadine

CAS No.: 924012-43-1

Centanafadine (EB-1020, EB1020)

Catalog No.: PC-27838Not For Human Use, Lab Use Only.

Centanafadine (EB-1020) is a potent triple reuptake inhibitor of reuptake transporters for norepinephrine (NET), dopamine (DAT) and serotonin (SERT) with IC50 of 6 nM, 38 nM and 83 nM respectively.

Packing	Price	Stock
5 mg	$98	In stock
10 mg	$148	In stock
25 mg	$258	In stock
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Biological Activity

Centanafadine (EB-1020) is a potent triple reuptake inhibitor of reuptake transporters for norepinephrine (NET), dopamine (DAT) and serotonin (SERT) with IC50 of 6 nM, 38 nM and 83 nM respectively.

Physicochemical Properties

M.Wt	209.29
Formula	C15H15N
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(1R,5S)-1-(Naphthalen-2-yl)-3-azabicyclo[3.1.0]hexane

References

1. Matuskey D, et al. J Psychopharmacol. 2023 Feb;37(2):164-171.

2. Bymaster FP, et al. Synapse 66: 522–532.

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Centanafadine (EB-1020, EB1020)

Biological Activity

Physicochemical Properties

References

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