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Chemical Structure : Chicago Sky Blue 6B
Catalog No.: PC-60881Not For Human Use, Lab Use Only.
A counterstain for background autofluorescence in fluorescence and immunofluorescence histochemistry, also is the first small molecule prion protein (PrP) ligand capable of inhibiting Aβ binding.
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A counterstain for background autofluorescence in fluorescence and immunofluorescence histochemistry, also is the first small molecule prion protein (PrP) ligand capable of inhibiting Aβ binding; inhibits Aβ binding and reduce prion levels was established in cell-based assays; also is a competitive VGLUT inhibitor without affecting plasma membrane transporters, shows antinociceptive effects in vivo; also is an allosteric inhibitor of macrophage migration inhibitory factor (MIF) with IC50 of 0.81 uM.
| M.Wt | 992.791 | |
| Formula | C34H24N6Na4O16S4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Risse E, et al. J Biol Chem. 2015 Jul 3;290(27):17020-8.
2. Yu G, et al. Behav Pharmacol. 2013 Dec;24(8):653-8.
3. He Z, et al. Behav Brain Res. 2013 Feb 15;239:172-6.
4. Bai F, et al. J Biol Chem. 2012 Aug 31;287(36):30653-63.
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