ChlaDUB1 inhibitor 27a

Chemical Structure : ChlaDUB1 inhibitor 27a

Catalog No.: PC-24201Not For Human Use, Lab Use Only.

ChlaDUB1 inhibitor 27a is a specific covalent inhibitor of bacterial chlamydial deubiquitinase 1 (ChlaDUB1) with IC50 of 0.97 uM, inhibits chlamydial growth with IC50 of 25.6 ug/mL.

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Biological Activity

ChlaDUB1 inhibitor 27a is a specific covalent inhibitor of bacterial chlamydial deubiquitinase 1 (ChlaDUB1) with IC50 of 0.97 uM, inhibits chlamydial growth with IC50 of 25.6 ug/mL.

Physicochemical Properties

M.Wt	396.41
Formula	C22H16N6O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Cyano N-((1-(2-phenyl acetyl) 1H-indazol-3-yl) methyl) pyrimidine 4-carboxamide

References

1. Zimmermann T, et al. J Med Chem. 2025 Feb 28. doi: 10.1021/acs.jmedchem.4c02464.

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