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Cibisatamab

Chemical Structure : Cibisatamab

CAS No.:

Cibisatamab (Anti-human CEACAM5 mAb, human IgG1-Kappa; RG-7802)

Catalog No.: PC-Ab1057Not For Human Use, Lab Use Only.

Cibisatamab (CEA-TCB, RO-6958688) is a novel bispecific antibody immunotherapy that effectively brings the cancer cells and cancer-killing T cells of the immune system together, triggers T cell killing of cancer cell lines expressing moderate to high levels of CEA at the cell surface. It is efficacious in poorly infiltrated tumors where it increases T-cell infiltration and generates a highly inflamed tumor microenvironment..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Cibisatamab (CEA-TCB, RO-6958688) is a novel bispecific antibody immunotherapy that effectively brings the cancer cells and cancer-killing T cells of the immune system together, triggers T cell killing of cancer cell lines expressing moderate to high levels of CEA at the cell surface. It is efficacious in poorly infiltrated tumors where it increases T-cell infiltration and generates a highly inflamed tumor microenvironment.

Physicochemical Properties

M.Wt
Formula Human IgG1-Kappa
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

References

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