Cilostamide | PDE3 inhibitor | Probechem Biochemicals

Chemical Structure : Cilostamide

CAS No.: 68550-75-4

Cilostamide (OPC3689, OPC-3689)

Catalog No.: PC-25901Not For Human Use, Lab Use Only.

Cilostamide (OPC3689) is a potent, selective PDE3 inhibitorwith IC50 of 27 nM and 50 nM for PDE3A and PDE3B, respectively, shows antithrombotic and anti-intimal hyperplastic activity.

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Biological Activity

Cilostamide (OPC3689) is a potent, selective PDE3 inhibitorwith IC50 of 27 nM and 50 nM for PDE3A and PDE3B, respectively, shows antithrombotic and anti-intimal hyperplastic activity.

Physicochemical Properties

M.Wt	342.44
Formula	C20H26N2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-Cyclohexyl-N-methyl-4-((2-oxo-1,2-dihydroquinolin-6-yl)oxy)butanamide

References

1. Sudo T, et al. Biochem Pharmacol. 2000 Feb 15;59(4):347-56.

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Cilostamide (OPC3689, OPC-3689)

Biological Activity

Physicochemical Properties

References

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