Chemical Structure : Cirsiliol
CAS No.: 34334-69-5
Catalog No.: PC-27992Not For Human Use, Lab Use Only.
Cirsiliol is a selective 5-lipoxygenase (5-LO) inhibitor with IC50 of 0.1 uM for 5-LO purified from rat basophilic leukemia cells, also binds and inhibits TYK2, inhibits ESCC growth in vitro and in vivo, also induces autophagy and mitochondrial apoptosis in osteosarcoma.
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|---|---|---|---|
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| 10 mg | $128 | In stock | |
| 25 mg | $218 | In stock | |
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Cirsiliol is a selective 5-lipoxygenase (5-LO) inhibitor with IC50 of 0.1 uM for 5-LO purified from rat basophilic leukemia cells, also binds and inhibits TYK2, inhibits ESCC growth in vitro and in vivo, also induces autophagy and mitochondrial apoptosis in osteosarcoma.
| M.Wt | 330.29 | |
| Formula | C17H14O7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy-4H-chromen-4-one |
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1. Kohno SW, et al. Adv Prostaglandin Thromboxane Leukot Res. 1985;15:217-9.
2. Yoshimoto T, et al. Biochem Biophys Res Commun. 1983 Oct 31;116(2):612-8.
3. Horie T, et al. J Med Chem. 1986 Nov;29(11):2256-62.

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