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Clevudine

Chemical Structure : Clevudine

CAS No.: 163252-36-6

Clevudine (L-FMAU)

Catalog No.: PC-28208Not For Human Use, Lab Use Only.

Clevudine (L-FMAU) is a nucleoside analog and non-competitive, reverse transcriptase inhibitor, inhibits both protein priming and DNA elongation, has potent anti-HBV activity.

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Biological Activity

Clevudine (L-FMAU) is a nucleoside analog and non-competitive, reverse transcriptase inhibitor, inhibits both protein priming and DNA elongation, has potent anti-HBV activity.

Physicochemical Properties

M.Wt 260.22
Formula C10H13FN2O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-((2S,3R,4S,5S)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

References

1. Asselah T, et al. Expert Opin Investig Drugs. 2008;17(12):1963-1974.

2. Yoo BC, et al. Hepatology. 2007;46(4):1041-1048.

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