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Clozapine N-oxide

Chemical Structure : Clozapine N-oxide

CAS No.: 34233-69-7

Clozapine N-oxide

Catalog No.: PC-45185Not For Human Use, Lab Use Only.

A pharmacologically inert metabolite of clozapine.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A pharmacologically inert metabolite of clozapine; a DREADD (designer receptors exclusively activated by designer drug) agonist.

Physicochemical Properties

M.Wt 342.8227
Formula C18H19ClN4O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-4-oxido-1-piperazinyl)-

References

1. Wess J, et al. Trends Pharmacol Sci. 2013 Jul;34(7):385-92.

2. Chang WH, et al. Prog Neuropsychopharmacol Biol Psychiatry. 1998 Jul;22(5):723-39.

3. Gomez JL, et al. Science. 2017 Aug 4;357(6350):503-507.

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