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Chemical Structure : ClpP inhibitor M21
Catalog No.: PC-35421Not For Human Use, Lab Use Only.
ClpP inhibitor M21 is a noncompetitive inhibitor of ClpP with IC50 of 41.42 uM, inhibits ClpP cleavage of SUc-LY-AMC substrate in a peptidase assay.
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ClpP inhibitor M21 is a noncompetitive inhibitor of ClpP with IC50 of 41.42 uM, inhibits ClpP cleavage of SUc-LY-AMC substrate in a peptidase assay.
ClpP inhibitor M21 alters α-toxin expression in a ClpP-dependent manner and attenuate S. aureus virulence via ClpP inhibition.
ClpP inhibitor M21 blocks the pathogenicity of infection in animal models.
| M.Wt | 385.452 | |
| Formula | C19H15NO4S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Gao P, et al. Proc Natl Acad Sci U S A. 2018 Jul 16. pii: 201720520.
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