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Chemical Structure : Col 003
Catalog No.: PC-62622Not For Human Use, Lab Use Only.
Col 003 is a small-molecule compound that inhibits the interaction of Hsp47 with collagen with IC50 of 1.8 uM, binds to the collagen-binding site on Hsp47.
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Col 003 is a small-molecule compound that inhibits the interaction of Hsp47 with collagen with IC50 of 1.8 uM, binds to the collagen-binding site on Hsp47; competitively inhibits the interaction and causes the inhibition of collagen secretion by destabilizing the collagen triple helix.
| M.Wt | 257.245 | |
| Formula | C14H11NO4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ito S, et al. J Biol Chem. 2017 Dec 8;292(49):20076-20085.
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