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Compound 11726148

Chemical Structure : Compound 11726148

CAS No.: 3010279-86-1

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Compound 11726148

Catalog No.: PC-72404Not For Human Use, Lab Use Only.

Compound 11726148 is a potent, specific antitubercular agent against Mycobacterium tuberculosis (M. tb) with MIC of 0.05 ug/mL, targets cytochrome bc1 complex.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Compound 11726148 is a potent, specific antitubercular agent against Mycobacterium tuberculosis (M. tb) with MIC of 0.05 ug/mL, targets cytochrome bc1 complex.
    Compound 11726148 demonstrated in vivo activity in an acute model of murine TB.

    Physicochemical Properties

    M.Wt 255.287
    Formula C11H11F2N3S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-(ethylthio)-7,8-difluoro-N-methylquinazolin-4-amine

    References

    1. Andréanne Lupien, et al. PLoS Pathog. 2020 Jan 23;16(1):e1008270.

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