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Cortexolone 17 alpha-propionate

Chemical Structure : Cortexolone 17 alpha-propionate

CAS No.: 19608-29-8

Cortexolone 17 alpha-propionate (Cortexolone 17α-propionate;CB-03-01;Clascoterone)

Catalog No.: PC-43500Not For Human Use, Lab Use Only.

Cortexolone 17 alpha-propionate (CB-03-01, Clascoterone) is a topical and peripherally selective androgen antagonist, displays a strong local antiandrogenic activity in hamster's flank organ test, does not exhibit antiandrogenic activity after subcutaneous injection in vivo.

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Biological Activity

Cortexolone 17 alpha-propionate (CB-03-01, Clascoterone) is a topical and peripherally selective androgen antagonist, displays a strong local antiandrogenic activity in hamster's flank organ test, does not exhibit antiandrogenic activity after subcutaneous injection in vivo.

Other Indication

Phase 3 Clinical

Physicochemical Properties

M.Wt
Formula C24H34O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Pregn-4-ene-3,20-dione, 21-hydroxy-17-(1-oxopropoxy)-

References

1. Celasco G, et al. Arzneimittelforschung. 2004;54(12):881-6.

2. Trifu V, et al. Br J Dermatol. 2011 Jul;165(1):177-83.

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