Cortistatin-14 | MRGPRX2 agonist | Probechem Biochemicals

Chemical Structure : Cortistatin-14

CAS No.: 186901-48-4

Catalog No.: PC-24414Not For Human Use, Lab Use Only.

Cortistatin-14 (CST-14) is a high affinity endogenous peptide agonist of MRGPRX2 (MrgX2) with EC50 of 25 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Cortistatin-14 (CST-14) is a high affinity endogenous peptide agonist of MRGPRX2 (MrgX2) with EC50 of 25 nM.

M.Wt	1720.03
Formula	C81H114N20O18S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Sequence: L-Lysinamide, L-prolyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-seryl-L-seryl-L-cysteinyl-, cyclic (2→13)-disulfide

1. Siehler S, et al. Mol Cell Endocrinol. 2008 May 14;286(1-2):26-34.

2. Ding Y, et al. Int Immunopharmacol. 2023 Apr;117:110003.

3. Robas N, et al. J Biol Chem. 2003 Nov 7;278(45):44400-4.