Cudetaxestat (BLD-0409, PAT-409) | Autotaxin inhibitor

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Chemical Structure : Cudetaxestat

CAS No.: 1782070-21-6

Cudetaxestat (BLD-0409, BLD0409, PAT-409)

Catalog No.: PC-73412Not For Human Use, Lab Use Only.

Cudetaxestat (BLD-0409, PAT-409) is a potent, selective, noncompetitive autotaxin (NPP2/ATX) inhibitor with IC50 of 4.95 nM (ATX), shows potential for indication of pulmonary fibrosis.

Packing	Price	Stock
5 mg	$158	In stock
10 mg	$248	In stock
25 mg	$428	In stock
50 mg	$728	In stock
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Purity & Documentation Purity: 99.29% (HPLC) Select Batch:

Biological Activity

Cudetaxestat (BLD-0409, PAT-409) is a potent, selective, noncompetitive autotaxin (NPP2/ATX) inhibitor with IC50 of 4.95 nM (ATX), shows potential for indication of pulmonary fibrosis.

Physicochemical Properties

M.Wt	482.327
Formula	C21H15Cl2F2N3O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-((2,6-dichloro-7-fluoro-1-(1-propyl-1H-pyrazol-4-yl)-1H-indol-3-yl)thio)-2-fluorobenzoic acid

References

1. Tan Z, et al. Expert Opin Ther Pat. 2021 May;31(5):421-434.

2. Jia Y, et al. Pharmaceuticals (Basel). 2021 Nov 22;14(11):1203.

3. Bano S, et al. Expert Opin Ther Pat. 2022 Apr 12:1-9.

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Cudetaxestat (BLD-0409, BLD0409, PAT-409)

Biological Activity

Physicochemical Properties

References

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