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D665-1412

Chemical Structure : D665-1412

CAS No.:

D665-1412

Catalog No.: PC-26969Not For Human Use, Lab Use Only.

D665-1412 is a specific small-molecule inhibitor of E3 ligase RNF126, blocks hypoxia-induced pexophagy, stabilizes peroxisomes, normalizes lipid metabolism, and reactivates hepatocytic differentiation markers, thereby redifferentiating HCC cells and suppressing tumor progression in vitro and in vivo.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

D665-1412 is a specific small-molecule inhibitor of E3 ligase RNF126, blocks hypoxia-induced pexophagy, stabilizes peroxisomes, normalizes lipid metabolism, and reactivates hepatocytic differentiation markers, thereby redifferentiating HCC cells and suppressing tumor progression in vitro and in vivo.

Physicochemical Properties

M.Wt
Formula
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

References

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