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D665-1412

Chemical Structure : D665-1412

CAS No.:

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D665-1412

Catalog No.: PC-26969Not For Human Use, Lab Use Only.

D665-1412 is a specific small-molecule inhibitor of E3 ligase RNF126, blocks hypoxia-induced pexophagy, stabilizes peroxisomes, normalizes lipid metabolism, and reactivates hepatocytic differentiation markers, thereby redifferentiating HCC cells and suppressing tumor progression in vitro and in vivo.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    D665-1412 is a specific small-molecule inhibitor of E3 ligase RNF126, blocks hypoxia-induced pexophagy, stabilizes peroxisomes, normalizes lipid metabolism, and reactivates hepatocytic differentiation markers, thereby redifferentiating HCC cells and suppressing tumor progression in vitro and in vivo.

    Physicochemical Properties

    M.Wt 290.79
    Formula C16H19ClN2O
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    References

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