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DB213

Chemical Structure : DB213

CAS No.: 209163-39-3

DB213 (RG-501)

Catalog No.: PC-62359Not For Human Use, Lab Use Only.

DB213 (RG-501) is a small molecule stimulator of HIV-1 frameshifting and inhibitor of viral replication.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

DB213 (RG-501) is a small molecule stimulator of HIV-1 frameshifting and inhibitor of viral replication; causes an imbalance in the ratio of Gag to Gag-Pol, and inhibits viral particle assembly.

Physicochemical Properties

M.Wt 478.328
Formula C18H36Cl4N6
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N1,N4-bis(3-(dimethylamino)propyl)terephthalimidamide tetrahydrochloride

References

1. Marcheschi RJ, et al. ACS Chem Biol. 2011 Aug 19;6(8):857-64.

2. Hung M, et al. J Virol. 1998 Jun;72(6):4819-24.

3. Wang Q, et al. J Pharm Biomed Anal. 2016 Jun 5;125:41-7.

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