CB1-IN-4 |CAS:1429239-98-4 Probechem Biochemicals

Chemical Structure : DBPR211

CAS No.: 1429239-98-4

DBPR211 (CB1-IN-4, BPRCB1184)

Catalog No.: PC-43210Not For Human Use, Lab Use Only.

DBPR211 (BPRCB1184, CB1-IN-4) is a potent, selective, peripherally restricted cannabinoid-1 (CB1) receptor antagonist with Ki of 0.3 nM, EC50 of 3.0 nM.

Packing	Price	Stock
5 mg	$298	In stock
10 mg	$458	In stock
25 mg	$728	In stock
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

DBPR211 (BPRCB1184, CB1-IN-4) is a potent, selective, peripherally restricted cannabinoid-1 (CB1) receptor antagonist with Ki of 0.3 nM, EC50 of 3.0 nM.
DBPR211 possess a low probability to cross BBB as a peripherally restricted CB1R antagonist, exhibits significant weight-loss efficacy in DIO mice.
DBPR211 also displays 163 clean off-target profiles and potential for treating obesity and the related metabolic syndrome.

Physicochemical Properties

M.Wt	751.6688
Formula	C33H31Cl2F3N6O3S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1H-Pyrazole-3-carboxamide, 1-(2,4-dichlorophenyl)-N-1-piperidinyl-4-[[(1-pyrrolidinylsulfonyl)amino]methyl]-5-[5-[2-[4-(trifluoromethyl)phenyl]ethynyl]-2-thienyl]-

References

1. Chang CP, et al. J Med Chem. 2013 Dec 27;56(24):9920-33.
2. Chun-Ping Chang, et al. Bioorg Med Chem. 2019 Jan 1;27(1):216-223.

DBPR211 (CB1-IN-4, BPRCB1184)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.