Chemical Structure : DFV890
CAS No.: 2271394-34-2
Catalog No.: PC-21282Not For Human Use, Lab Use Only.
DFV890 (NVP-DFV890, IFM-2427) is a potent, selective and orally active inhibitor of NLRP3 inflammasome, directly binds to NLRP3 and locks the protein in an inactive conformation, prevents NLRP3 inflammasome assembly in response to sterile danger signals.
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DFV890 (NVP-DFV890, IFM-2427) is a potent, selective and orally active inhibitor of NLRP3 inflammasome, directly binds to NLRP3 and locks the protein in an inactive conformation, prevents NLRP3 inflammasome assembly in response to sterile danger signals.
M.Wt | 420.55 | |
Formula | C19H24N4O3S2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(R)-N'-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-2-(2-hydroxypropan-2-yl)thiazole-5-sulfonimidamide |
1. Patent WO2020010118A1.
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