You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-Diglyceride Acyltransferase (DGAT)-DGAT2 inhibitor 2
DGAT2 inhibitor 2

Chemical Structure : DGAT2 inhibitor 2

CAS No.:

DGAT2 inhibitor 2

Catalog No.: PC-63472Not For Human Use, Lab Use Only.

DGAT2 inhibitor 2 is a novel potent, selective DGAT2 inhibitor with IC50 of 6 nM (hDGAT2), shows no significant activity for DGAT1 (IC50>20 uM).

Packing Price Stock Quantity
25 mg Get quote
100 mg Get quote
250 mg Get quote
1 g Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

DGAT2 inhibitor 2 is a novel potent, selective DGAT2 inhibitor with IC50 of 6 nM (hDGAT2), shows no significant activity for DGAT1 (IC50>20 uM); shows effective reduction of newly synthesized TG appearing in plasma in acute rodent model.

Physicochemical Properties

M.Wt 496.981
Formula C26H22ClFN2O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(2-chlorophenyl)-1-(4-fluorophenyl)-N-(3-methyl-1,1-dioxidotetrahydrothiophen-3-yl)-1H-indole-6-carboxamide

References

1. McLaren DG, et al. Cell Metab. 2018 Apr 20. pii: S1550-4131(18)30245-6.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: