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Chemical Structure : DIDS
Catalog No.: PC-61230Not For Human Use, Lab Use Only.
DIDS is a small molecule inhibitor of RAD51-mediated homologous recombination.
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DIDS is a small molecule inhibitor of RAD51-mediated homologous recombination.
DIDS inhibits repair of activation-induced cytidine deaminase (AID)-initiated DNA breaks, induces apoptosis, and promotes cytotoxicity preferentially in AID-expressing human CLL;.
DIDS strongly inhibits T1D development in NOD mice.
| M.Wt | 516.483 | |
| Formula | C16H10N2Na2O7S4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ratiu JJ, et al. J Immunol. 2017 Jun 1;198(11):4255-4267.
2. Lamont KR, et al. Exp Med. 2013 May 6;210(5):1021-33.
3. Dinnen RD, et al. Mol Cancer Ther. 2013 Dec;12(12):2792-803.
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