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Chemical Structure : DMXAA
CAS No.: 117570-53-3
Catalog No.: PC-42754Not For Human Use, Lab Use Only.
DMXAA (ASA-404, Vadimezan) is a vascular disrupting agent (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 uM, also is a partial STING agonist, competes for human STING activation and STING dependent innate immune pathways.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $88 | In stock | |
| 25 mg | $138 | In stock | |
| 50 mg | $218 | In stock | |
| 100 mg | $358 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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DMXAA (ASA-404, Vadimezan) is a vascular disrupting agent (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 uM, also is a partial STING agonist, competes for human STING activation and STING dependent innate immune pathways.
| M.Wt | 282.2906 | |
| Formula | C17H14O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: 6.5 mg/mL |
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| Chemical Name/SMILES |
9H-Xanthene-4-acetic acid, 5,6-dimethyl-9-oxo- |
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1. Phillips RM. Biochem Pharmacol. 1999 Jul 15;58(2):303-10.
2. Prantner D, et al. J Biol Chem. 2012 Nov 16;287(47):39776-88.
3. Shirey KA, et al. J Leukoc Biol. 2011 Mar;89(3):351-7.
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