DNDI-6148 | Visceral leishmaniasis inhibitor

Chemical Structure : DNDI-6148

CAS No.: 2243909-59-1

DNDI-6148 (DNDI6148)

Catalog No.: PC-26662Not For Human Use, Lab Use Only.

DNDI-6148 is a potent, selective inhibitor of Visceral leishmaniasis (VL) with EC50 of 1.8 uM and 1.4 uM for intramacrophage L. infantum and L. donovani, inhibits Leishmania cleavage and polyadenylation specificity factor (CPSF3) endonuclease.

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5 mg	$428	In stock
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Biological Activity

Physicochemical Properties

M.Wt	335.13
Formula	C16H14BN5O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)-5-methyl-1-(pyridin-2-yl)-1H-1,2,3-triazole-4-carboxamide

References

1. Mowbray CE, et al. J Med Chem. 2021 Nov 11;64(21):16159-16176.

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DNDI-6148 (DNDI6148)

Biological Activity

Physicochemical Properties

References

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