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DSM186

Chemical Structure : DSM186

CAS No.: 1282041-96-6

DSM186 (DSM 186)

Catalog No.: PC-49850Not For Human Use, Lab Use Only.

DSM186 (DSM 186) is a high potent A. baumannii DHODH (AbDHODH) inhibitor with IC50 of 28 nM, has MIC <1 ug/mL against geographically diverse A. baumannii strains, including meropenem-resistant isolates.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

DSM186 (DSM 186) is a high potent A. baumannii DHODH (AbDHODH) inhibitor with IC50 of 28 nM, has MIC <1 ug/mL against geographically diverse A. baumannii strains, including meropenem-resistant isolates.

Physicochemical Properties

M.Wt 350.31
Formula C13H11F5N4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

7-methyl-N-(4-(pentafluoro-l6-sulfaneyl)phenyl)imidazo[1,2-a]pyrimidin-5-amine

References

1. Russo TA, et al. Proc Natl Acad Sci U S A. 2022 Dec 20;119(51):e2213116119.

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