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Chemical Structure : DSM502
Catalog No.: PC-20265Not For Human Use, Lab Use Only.
DSM502 (DSM 502) is a potent, selective inhibitor of P. falciparum and P. vivax DHODH with IC50 of 20 and 14 nM, respectively.
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DSM502 (DSM 502) is a potent, selective inhibitor of P. falciparum and P. vivax DHODH with IC50 of 20 and 14 nM, respectively.
DSM502 displays high potency against Pf3D7 parasites in whole cell assays (IC50=14 nM).
DSM502 displays no inhibitory activities on mammalian DHODHs (IC50>100 uM, hDHODH,mDHODH,rDHODH and dDHODH).
| M.Wt | 323.32 | |
| Formula | C16H16F3N3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Sreekanth Kokkonda, et al. J Med Chem. 2020 May 14;63(9):4929-4956.
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