Daminozide

Chemical Structure : Daminozide

CAS No.: 1596-84-5

Catalog No.: PC-27219Not For Human Use, Lab Use Only.

Daminozide is a plant growth regulator and selective inhibitor of KDM2/7 JmjC subfamily with IC50 of 1.5 uM, 0.55 uM and 2.1 uM for KDM2A, PHF8 and KIAA1718 respectively.

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1 g	$38	In stock
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Biological Activity

Daminozide is a plant growth regulator and selective inhibitor of KDM2/7 JmjC subfamily with IC50 of 1.5 uM, 0.55 uM and 2.1 uM for KDM2A, PHF8 and KIAA1718 respectively.
Daminozide is >100-fold selective over KDM3A and other demethylases.
Daminozide is a competitive inhibitor with respect to 2OG (Ki=1.97 uM), but not peptide substrates.

Physicochemical Properties

M.Wt	160.17
Formula	C6H12N2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(Dimethylamino)succinamic acid

References

1. Rose NR, et al. J Med Chem. 2012 Jul 26;55(14):6639-43.

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Daminozide

Biological Activity

Physicochemical Properties

References

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