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Chemical Structure : Darunavir
CAS No.: 206361-99-1
Catalog No.: PC-45164Not For Human Use, Lab Use Only.
A potent, selective HIV-1 protease inhibitor that is extremely potent against laboratory HIV-1 strains and primary clinical isolates with IC50 of 3 nM, IC90 of 9 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $212 | In stock | |
| 50 mg | $784 | In stock |
Bulk size, bulk discount!
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A potent, selective HIV-1 protease inhibitor that is extremely potent against laboratory HIV-1 strains and primary clinical isolates with IC50 of 3 nM, IC90 of 9 nM; blockes the infectivity and replication of HIV-1(NL4-3) variants with IC50 of 3-29 nM, also potent against multi-PI-resistant clinical HIV-1 variants isolated from patients; used to treat and prevent HIV/AIDS.
HIV Infection
Approved
| M.Wt | 547.6636 | |
| Formula | C27H37N3O7S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Carbamic acid, N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ester |
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1. Surleraux DL, et al. J Med Chem. 2005 Mar 24;48(6):1813-22.
2. Koh Y, et al. Antimicrob Agents Chemother. 2003 Oct;47(10):3123-9.
3. King NM, et al. J Virol. 2004 Nov;78(21):12012-21.
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