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Chemical Structure : Daxdilimab
Catalog No.: PC-38814Not For Human Use, Lab Use Only.
Daxdilimab (HZN-7734) is a fully human monoclonal antibody that binds to the ILT7 protein on the surface of plasmacytoid dendritic cells (pDCs) and recruits effector cells, such as natural killer (NK) cells, that help to kill pDCs.
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Daxdilimab (HZN-7734) is a fully human monoclonal antibody that binds to the ILT7 protein on the surface of plasmacytoid dendritic cells (pDCs) and recruits effector cells, such as natural killer (NK) cells, that help to kill pDCs.
ILT7 (CD85g, LILRA4) is a protein found specifically on pDCs, pDC depletion with daxdilimab prevents the production of type 1 interferons, pro-inflammatory cytokines.
Isotype: IgG1-lambda.
Anti-[human LILRA4 (leukocyte immunoglobulin like receptor A4, ILT7, CD85g)], human monoclonal antibody.
| M.Wt | ||
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| Appearance | Solid | |
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| Solubility |
10 mM in DMSO |
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