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Decursin

Chemical Structure : Decursin

CAS No.: 5928-25-6

Decursin ((+)-Decursin)

Catalog No.: PC-20618Not For Human Use, Lab Use Only.

Decursin ((+)-Decursin) is a potent anti-tumor agent and a potent protein kinase C activator, induces apoptosis and cell cycle arrest at G1 phase.

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Biological Activity

Decursin ((+)-Decursin) is a potent anti-tumor agent and a potent protein kinase C activator, induces apoptosis and cell cycle arrest at G1 phase, inhibits CYP2J2 with IC50 of 6.9 uM.

Physicochemical Properties

M.Wt 328.36
Formula C19H20O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

C/C(C)=C\C(O[C@H](C(C)(C)O1)CC2=C1C=C(O3)C(C=CC3=O)=C2)=O

References

1. Yim D, et al. Cancer Res. 2005 Feb 1;65(3):1035-44.

2. Jung SY, et al. J Cell Biochem. 2012 May;113(5):1478-87.

3. Ahn KS, et al. Planta Med. 1996 Feb;62(1):7-9.

4. Lee B, et al. Food Chem Toxicol 70:94–99.

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