Deruxtecan | DXd drug-linker conjugate for ADC

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Chemical Structure : Deruxtecan

CAS No.: 1599440-13-7

Deruxtecan (MC-GGFG-DXd)

Catalog No.: PC-28473Not For Human Use, Lab Use Only.

Deruxtecan (MC-GGFG-DXd) is an ADC drug-linker conjugate composed of DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing PROTAC Trastuzumab deruxtecan and Patritumab deruxtecan.

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25 mg	$138	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Physicochemical Properties

M.Wt	1034.07
Formula	C52H56FN9O13
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((S)-10-Benzyl-1-(((1S,9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl)amino)-1,6,9,12,15-pentaoxo-3-oxa-5,8,11,14-tetraazahexadecan-16-yl)-6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamide

References

1. Ogitani Y, et al. Cancer Sci. 2016 Jul;107(7):1039-46.

2. NOGUCHI, Shigeru, et al. WO2017002776A1.

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Deruxtecan (MC-GGFG-DXd)

Biological Activity

Physicochemical Properties

References

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