Chemical Structure : Dihydroartemisinin
CAS No.: 71939-50-9
Catalog No.: PC-27967Not For Human Use, Lab Use Only.
Dihydroartemisinin (DHA, Artenimol, β-Dihydroartemisinin) is an antimalarial agent and semi-synthetic derivative of Artemisinin, also has anti-inflammatory and anti-cancer effect, directly binds to YTHDF2 and inhibits its function, induces autophagy by inhibiting NF-κB activation, induces iron-dependent cell death (ferroptosis) in tumor cells.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 100 mg | $38 | In stock | |
| 500 mg | $88 | In stock | |
| 1 g | Get quote |
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Dihydroartemisinin (DHA, Artenimol, β-Dihydroartemisinin) is an antimalarial agent and semi-synthetic derivative of Artemisinin, also has anti-inflammatory and anti-cancer effect, directly binds to YTHDF2 and inhibits its function, induces autophagy by inhibiting NF-κB activation, induces iron-dependent cell death (ferroptosis) in tumor cells.
Dihydroartemisinin exerts cytotoxic effects and inhibits hypoxia inducible factor-1alpha activation in C6 glioma cells.
Dihydroartemisinin shows selective inhibition of ovarian cancer cell growth, apoptosis induction, and G2 arrest
Dihydroartemisinin promotes neurological rehabilitation after ischemic stroke by targeting TAK1-CREB1 signaling pathway to inhibit ferroptosis.
Dihydroartemisinin inhibits Epstein-Barr virus reactivation and replication targeting lytic proteins.
DHA significantly alleviated arthritis and inhibited neutrophil extracellular traps (NETs) formation both in vivo and in vitro.
| M.Wt | 284.35 | |
| Formula | C15H24O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-Trimethyldecahydro-3H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-ol |
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1. Lin AJ, et al. J Med Chem. 1989 Jun;32(6):1249-52.
2. Ye S, et al. Mol Immunol. 2026 Sep;197:144-157.
3. Moore JC, et al. Cancer Lett. 1995 Nov 27;98(1):83-7.
4. Ooko E, et al. Phytomedicine. 2015 Oct 15;22(11):1045-54.

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