Chemical Structure : Dimethyl fumarate
Catalog No.: PC-45182Not For Human Use, Lab Use Only.
Dimethyl fumarate (DMF.
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Dimethyl fumarate (DMF;BG-12) exerts anti-inflammatory and pro-metabolic effects in a variety of cell types; an effective novel treatment for multiple sclerosis; activates the Nrf2 pathway and has been identified as a nicotinic acid receptor agonist in vitro.
Multiple Sclerosis
Approved
M.Wt | 144.1253 | |
Formula | C6H8O4 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: 9.6 mg/mL |
1. Peng H, et al. J Biol Chem. 2012 Aug 10;287(33):28017-26.
2. Ashrafian H, et al. Cell Metab. 2012 Mar 7;15(3):361-71.
3. Scannevin RH, et al. J Pharmacol Exp Ther. 2012 Apr;341(1):274-84.
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