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Chemical Structure : Droloxifene
CAS No.: 82413-20-5
Catalog No.: PC-70133Not For Human Use, Lab Use Only.
Droloxifene (3-Hydroxytamoxifen; FK-435) is a nonsteroidal selective estrogen receptor modulator (SERM) that shows 10- to 60-fold increased affinity for the estrogen receptor compared with Tamoxifen.
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Droloxifene (3-Hydroxytamoxifen; FK-435) is a nonsteroidal selective estrogen receptor modulator (SERM) that shows 10- to 60-fold increased affinity for the estrogen receptor compared with Tamoxifen.
Droloxifene has reduced partial estrogen agonistic activity.
| M.Wt | 387.52 | |
| Formula | C26H29NO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(Z)-4-(1-(4-(2-aminoethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenol |
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1. Rauschning W, et al. Breast Cancer Res Treat. 1994;31(1):83-94.
2. Hasmann M, et al. Cancer Lett. 1994 Sep 15;84(2):101-16.
3. Leng Y, et al. Eur J Pharmacol. 2000 Dec 8;409(2):123-31.
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