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Dual DRAK1 and DRAK2 inhibitor 1

Chemical Structure : Dual DRAK1 and DRAK2 inhibitor 1

CAS No.: 1629227-34-4

Dual DRAK1 and DRAK2 inhibitor 1

Catalog No.: PC-38221Not For Human Use, Lab Use Only.

Dual DRAK1 and DRAK2 inhibitor 1 is a potent, dual DRAK2/1 inhibitor Kd value of 9/5 nM, respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Dual DRAK1 and DRAK2 inhibitor 1 is a potent, dual DRAK2/1 inhibitor Kd value of 9/5 nM, respectively.
Dual DRAK1 and DRAK2 inhibitor 1 also is a functional inhibitor of DRAK2/1 enzymatic activity with IC50 of 0.86 and 2.25 uM.
Dual DRAK1 and DRAK2 inhibitor 1 is a chemical tool compound to study DRAK1 and DRAK2 biology.

Physicochemical Properties

M.Wt 396.505
Formula C22H24N2O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(5-(3,4-dimethoxyphenyl)thieno[2,3-b]pyridin-3-yl)cyclohexanecarboxamide

References

1. Ling-Jie Gao, et al. J Med Chem. 2014 Sep 25;57(18):7624-43.

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