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Dynein inhibitor 20

Chemical Structure : Dynein inhibitor 20

CAS No.: 2663697-25-2

Dynein inhibitor 20

Catalog No.: PC-73232Not For Human Use, Lab Use Only.

Dynein inhibitor 20 is a small moelcule inhibitor of S. cerevisiae dynein by engaging the regulatory ATPase sites in AAA3 and AAA4 domains.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Dynein inhibitor 20 is a small moelcule inhibitor of S. cerevisiae dynein by engaging the regulatory ATPase sites in AAA3 and AAA4 domains.
Dynein inhibitor 20 does not interact with dynein's main catalytic site in the AAA1 domain.

Physicochemical Properties

M.Wt 481.734
Formula C22H14BrClN4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-(3-bromophenoxy)-2-(1-(4-chlorophenyl)cyclopropyl)-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile

References

1. Cristina C Santarossa, et al. Cell Chem Biol. 2021 Oct 21;28(10):1460-1473.e15.

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