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Chemical Structure : E-5842 hydrochloride
Catalog No.: PC-63204Not For Human Use, Lab Use Only.
E-5842 is a preferential sigma-1 receptor ligand, demonstrates potential atypical antipsychotic effects in vivo.
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E-5842 hydrochloride (E5842) is a preferential sigma-1 receptor ligand, demonstrates potential atypical antipsychotic effects in vivo.
E-5842 increases phospholipase C (PLC) activity in the striatum and the hippocampus, increased levels of Fos in the medial prefrontal cortex and the nucleus accumbens in rat forebrain.
| M.Wt | 336.839 | |
| Formula | C17H22ClFN4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Sánchez-Arroyos R, et al. Eur J Pharmacol. 1999 Jul 28;378(1):31-7.
2. Romero G, et al. Neurosci Lett. 2000 Sep 1;290(3):189-92.
3. Guitart X, et al. Neuropsychopharmacology. 2000 Nov;23(5):539-46.
4. Guitart X, et al. Eur J Pharmacol. 1998 Dec 18;363(2-3):127-30.
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