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Chemical Structure : EC-11716
Catalog No.: PC-72693Not For Human Use, Lab Use Only.
EC-11716 (EC/11716) is a novel mycobacterium tuberculosis gyrase inhibitor with potent anti-tubercular activity (MIC 0.38 uM, M. tuberculosis H37Rv).
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EC-11716 (EC/11716) is a novel mycobacterium tuberculosis gyrase inhibitor with potent anti-tubercular activity (MIC 0.38 uM, M. tuberculosis H37Rv).
EC/11716 is active against M. abscessus subspecies and clinical isolates, maintains comparable activity against a panel of clinical isolates covering the M. abscessus complex.
EC/11716 is effective against M. abscessus biofilms (MIC 0.78 uM), with better bactericidal activity against biofilms than moxifloxacin.
EC/11716 is active against M. abscessus in vivo.
| M.Wt | 457.959 | |
| Formula | C23H28ClN5O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Uday S Ganapathy, et al. Antimicrob Agents Chemother. 2021 Nov 17;65(12):e0151421.
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