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Chemical Structure : EG00229 free base
Catalog No.: PC-35130Not For Human Use, Lab Use Only.
EG00229 is a specific inhibitor of neuropilin-1 (NRP1)/VEGF-A interaction, inhibits the binding of biotinylated VEGFA to NRP1 with IC50 of 8 uM.
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EG00229 is a specific inhibitor of neuropilin-1 (NRP1)/VEGF-A interaction, inhibits the binding of biotinylated VEGFA to NRP1 with IC50 of 8 uM; also demonstrates to have functional effects on cell-migration and VEGF-R2 phosphorylation.
| M.Wt | 497.563 | |
| Formula | C17H19N7O5S3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Powell J, et al. J Med Chem. 2018 May 10;61(9):4135-4154.
2. Jarvis A, et al. J Med Chem. 2010 Mar 11;53(5):2215-26.
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