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Chemical Structure : EHP-101
CAS No.: 1818428-24-8
Catalog No.: PC-38051Not For Human Use, Lab Use Only.
EHP-101 (Etrinabdione, VCE-004.8) is an orally active, specific PPARγ and CB2 receptor dual agonist.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $248 | In stock | |
| 10 mg | $398 | In stock | |
| 50 mg | $798 | In stock | |
| 100 mg | $1280 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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EHP-101 (Etrinabdione, VCE-004.8) is an orally active, specific PPARγ and CB2 receptor dual agonist.
EHP-101 could prevent macrophage infiltration as well as the expression of Tenascin C (TNC), vascular cell adhesion molecule 1 (VCAM1), and the α-smooth muscle actin (SMA).
EHP-101 also prevent the reduced expression of vascular CD31 typical of skin fibrosis.
EHP-101 alleviates bleomycin-induced skin and lung fibrosis in mice.
| M.Wt | 433.592 | |
| Formula | C28H35NO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(1'R,6'R)-3-(benzylamino)-6-hydroxy-3'-methyl-4-pentyl-6'-(prop-1-en-2-yl)-[1,1'-bi(cyclohexane)]-2',3,6-triene-2,5-dione |
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1. García-Martín A, et al. Biochem Pharmacol. 2018 Nov;157:304-313.
2. Navarrete C, et al. Neurobiol Dis. 2020 Sep;143:104994.
3. García-Martín A, et al. Biomed Pharmacother. 2021 Oct;142:112007.
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