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Chemical Structure : ELN484228
CAS No.: 312-63-0
Catalog No.: PC-63274Not For Human Use, Lab Use Only.
ELN484228 is a small molecule binder of α-synuclein that shows protective effect in cellular models of αSyn-mediated vesicular dysfunction.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $88 | In stock | |
| 50 mg | $158 | In stock | |
| 100 mg | $258 | In stock | |
| 250 mg | Get quote | ||
| 1 g | Get quote |
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ELN484228 is a small molecule binder of α-synuclein that shows protective effect in cellular models of αSyn-mediated vesicular dysfunction.
ELN484228 rescues α-synuclein-induced disruption of vesicle trafficking and dopaminergic neuronal loss and neurite retraction most likely by reducing the amount of α-synuclein targeted to sites of vesicle mobilization such as the synapse in neurons or the site of bead engulfment in microglial cells.
ELN484228 shows potential therapeutic strategy for Parkinson's disease.
| M.Wt | 251.28 | |
| Formula | C12H10FNO2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-(4-Fluorophenyl)-benzenesulfonamide |
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1. Tóth G, et al. PLoS One. 2014 Feb 14;9(2):e87133.
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