ESC1002755 | 17β-HSD10 inhibitor | Probechem Biochemicals

Chemical Structure : ESC1002755

ESC1002755 (ESC-1002755)

Catalog No.: PC-24917Not For Human Use, Lab Use Only.

ESC1002755 is a highly potent 17β-Hydroxysteroid type 10 (17β-HSD10) inhibitor with IC50 of 19 nM in biochemical assays, inhibits cellular 17β-HSD10 activity with EC50 of 28 nM in stable HEK 293 cell line overexpressing 17β-HSD10.

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Biological Activity

Physicochemical Properties

M.Wt	383.89
Formula	C21H18ClNO2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-(3-chlorothiophen-2-yl)(2-(3'-hydroxy-[1,1'-biphenyl]-2-yl)pyrrolidin-1-yl)methanone

References

1. Aitken L, et al. ACS Chem Biol. 2025 Jun 18. doi: 10.1021/acschembio.5c00110.

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ESC1002755 (ESC-1002755)

Biological Activity

Physicochemical Properties

References

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