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Chemical Structure : Efonidipine hydrochloride
Catalog No.: PC-43071Not For Human Use, Lab Use Only.
Efonidipine (NZ-105) is a potent, dual T-type and L-type calcium channel blocker, exhibits antihypertensive effect through vasodilatation.
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Efonidipine (NZ-105) is a potent, dual T-type and L-type calcium channel blocker, exhibits antihypertensive effect through vasodilatation; increases coronary blood flow by blocking L & T-type calcium channels and attenuates myocardial ischaemia, lowers blood pressure in cerebral resistance vessels and prevents hypertension induced brain damage; increases glomerular filtration rate without increasing intra-glomerular pressure and filtration fraction.
| M.Wt | 668.1161 | |
| Formula | C34H39ClN3O7P | |
| Appearance | Solid | |
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| Solubility |
DMSO: 8.5 mg/mL |
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1. Masuda Y, et al. Arch Int Pharmacodyn Ther. 1990 Mar-Apr;304:247-64.
2. Tamura T, et al. Naunyn Schmiedebergs Arch Pharmacol. 1991 Apr;343(4):405-10.
3. Shudo C, et al. Gen Pharmacol. 1994 Nov;25(7):1451-8.
4. Yamashita T, et al. Jpn J Pharmacol. 1991 Nov;57(3):337-48.
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