Enfiborole

Chemical Structure : Enfiborole

Catalog No.: PC-26325Not For Human Use, Lab Use Only.

Enfiborole is a potent small molecule inhibitor of Trypanosoma congolense (T. congolense) and Trypanosoma vivax (T. vivax) parasites with IC50 of 0.14 nM and 0.07 nM respectively.

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Biological Activity

Enfiborole is a potent small molecule inhibitor of Trypanosoma congolense (T. congolense) and Trypanosoma vivax (T. vivax) parasites with IC50 of 0.14 nM and 0.07 nM respectively.

Physicochemical Properties

M.Wt	450.22
Formula	C21H22BF3N2O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(6-(trifluoromethyl)pyridin-3-yl)methyl (1-hydroxy-7-methyl-1,3-dihydrobenzo[c][1,2]oxaborole-6-carbonyl)-L-valinate

References

1. Akama T, et al. Bioorg Med Chem Lett. 2018 Jan 1;28(1):6-10.

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Enfiborole

Biological Activity

Physicochemical Properties

References

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