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Chemical Structure : EphB3-IN-1
Catalog No.: PC-62858Not For Human Use, Lab Use Only.
EphB3-IN-1 is the first potent, selective inhibitor of EphB3 that exhibits inhibiting EphB3 autophosphorylation in cells with IC50 of 3 nM.
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EphB3-IN-1 is the first potent, selective inhibitor of EphB3 that exhibits inhibiting EphB3 autophosphorylation in cells with IC50 of 3 nM; causes foremost inhibition of EphB3 in a panel of 98 kinases, except for RIPK2 and PHKG2; abolishes the EphB3 autophosphorylation at Y608 and Y614 at 100 nM.
| M.Wt | 363.198 | |
| Formula | C16H12Cl2N4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kung A, et al. J Am Chem Soc. 2016 Aug 24;138(33):10554-60.
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