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Chemical Structure : Erg6 inhibitor H55
Catalog No.: PC-20789Not For Human Use, Lab Use Only.
Erg6 inhibitor H55 is an allosteric inhibitor of fungal-specific C-24 sterol methyltransferase (Erg6), potently inhibits C. albicans hyphal formation in multiple cultural conditions.
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Erg6 inhibitor H55 is an allosteric inhibitor of fungal-specific C-24 sterol methyltransferase (Erg6), potently inhibits C. albicans hyphal formation in multiple cultural conditions.
H55 monotherapy exhibits therapeutic efficacy in mouse models of azole-resistant candidiasis.
H55 treatment increases the accumulation of zymosterol, the substrate of C-24 sterol methyltransferase (Erg6).
| M.Wt | 517.45 | |
| Formula | C26H21BrN4OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Jin X, et al. Cell Chem Biol. 2023 May 2:S2451-9456(23)00116-2.
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