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Chemical Structure : Evogliptin
Catalog No.: PC-61445Not For Human Use, Lab Use Only.
Evogliptin (DA1229) is a potent, long acting, reversible and competitive DPP-4 inhibitor with IC50 of 0.9 nM.
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Evogliptin (DA1229) is a potent, long acting, reversible and competitive DPP-4 inhibitor with IC50 of 0.9 nM.
Evogliptin (DA1229) displays >600-fold selectivity over DPP8 and DPP9.
Evogliptin (DA1229) increases levels of plasma GLP-1 and insulin, and lowers blood glucose levels in mice (0.1-3 mg/kg).
| M.Wt | 401.43 | |
| Formula | C19H26F3N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kim MK, et al. Life Sci. 2012 Jan 2;90(1-2):21-9.
2. Kim HJ, et al. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3809-12.
3. Kim TH, et al. Eur J Pharmacol. 2016 Jan 15;771:65-76.
4. Chae YN, et al. PLoS One. 2015 Dec 3;10(12):e0144064.
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