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Exenatide acetate

Chemical Structure : Exenatide acetate

CAS No.: 914454-01-6

Exenatide acetate (Exendin-4 acetate)

Catalog No.: PC-43539Not For Human Use, Lab Use Only.

Exenatide acetate (Exendin-4 acetate) is the acetate of Exenatide, which is highly potent, long-acting glucagon-like peptide-1 receptor (GLP-1) agonist with IC50 of 3.22 nM..

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Biological Activity

Exenatide acetate (Exendin-4 acetate) is the acetate of Exenatide, which is highly potent, long-acting glucagon-like peptide-1 receptor (GLP-1) agonist with IC50 of 3.22 nM.

Diabetes

Phase 3 Clinical

Physicochemical Properties

M.Wt 4246.624
Formula C186H286N50O62S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO

Chemical Name/SMILES

L-Serinamide, L-histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isole

References

1. Eng J, et al. J Biol Chem. 1992 Apr 15;267(11):7402-5.

2. Fidan-Yaylalı G, et al. Tumour Biol. 2016 Feb;37(2):2647-53.

3. Schepp W, et al. Eur J Pharmacol. 1994 Oct 14;269(2):183-91.

4. Doyle ME, et al. Regul Pept. 2003 Jul 15;114(2-3):153-8.

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